the lost item pool, gold, orange, yellow, cross, pope, hat, A familiar the follows Isaac and fires random tears, Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc, * item room, treasure room, item room pool, purple, Upon use, opens all closed doors in the current room, including the ones which require a key to enter and secret room doors, Can be used to open the golden door that appears in the Dark Room or the Chest, Cannot be used to escape the Mom's Foot boss, open angel/devil rooms, or open the door to the Blue Womb floor, UNLOCK: Unlock this item by collecting both Key Pieces #1 & #2 for the first time, * key master pool, key beggar pool, key judgement pool, item room, treasure room, item room pool, Flies spawned from a Mulligan dying, When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies in close proximity and send a wave of spikes across the room in the direction you are facing, The enemies in close range will take 5 damage then have a poison over time effect which deals your tear damage 4 or 6 times, The spike wave will deal 10 damage to any enemies in contact with it. 1 Change Note Created by. While playing as him Anima Sola will always target Dark Esau. slow, shrink, fear), Spider Mod will also randomly drop battery consumables or blue spiders when a room is completed, For the sake of simplicity for players, all damage values displayed are multiplied by 10 and rounded to the nearest number, This item is a reference to Spider853, creator of Spidermod for the original game and one of the lead developers that worked on Rebirth and its DLCs, *, robot, red, grey, gray, silver, metal, antenna, A familiar that follows Isaac and blocks tears, If a tear hits Farting Baby, there is a 10% chance for it to fart, with 3 possible effects: Charm, Poison or Knock back, Charm deals 5 damage. The spear cannot be thrown like Mom's Knife but deals damage while it is in contact with an enemy, *, grey, silver, sword, dagger, blade, knife, Tears now have a random chance to become sticky bombs, which will attach to enemies and explode after a few seconds, The bomb explosion deals your tear damage + 60, REPENTANCE - Explosivo tears now deal damage upon impact, When picked up, drops between 1-6 random pickups on the floor, Causes all item pedestals to be chosen from a random item pool instead of the pre-defined ones which normally exist, Fixed item drops won't be replaced - e.g. If you haven't unlocked Holy Mantle for The Lost yet, you won't gain the effect after touching a white fire so be careful! One exception to this is if you are playing as Lazarus or have Lazarus' Rags - you will respawn in the same room and get the kill, Plan C is 5 times rarer than other items in the same item pool, making it less likely to appear, UNLOCK: Unlock this item by defeating Greedier Mode with Lazarus, Item Pool: Shop, Devil Room, Curse Room, Red Chest, Demon Beggar, When used, the D1 duplicates 1 random pickup in the current room. Can only happen once per room, Visually this is almost identical to the Guardian Angel item, but without a face, UNLOCK: Unlock this item by beating Blue Womb (Hush) with The Lost, A white orbiting fly which deals 3 contact damage per tick to enemies, This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone, Item Pool: Item Room, Greed Mode Item Room, Key Beggar. shop room pool, shop item pool,red, robot, head, cube, REPENTANCE - This item has been reworked. You get a couple of seconds of invincibility to move away after, The main benefit of this Soul Stone is that it automatically activates if you die, meaning it is effectively an extra passive life while held, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Lazarus, Activates the D6 and D20 effects, rerolling all items and pickups in the room. You can't use the Red Key to leave this room, The Red Key can be used to open the secret room in the Home floor, which is the method for unlocking alternative 'Tainted' characters, UNLOCK: Unlock this item by opening Mom's Box in the Home floor, Item Pool: Secret Room, Red Chest, Curse Room, Key Beggar, Mom's Chest. ), Doesn't show the location of Secret or Super Secret rooms, Room icons will not show if a Curse of the Lost is in effect on the current floor, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Heals one red heart container when picked up, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow. the lost item pool, brown, white, cross, * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, white, A beggar who follows Isaac around and automatically picks up nearby coins, After picking up 6 coins he will drop a random pickup, e.g. The effect is weaker than normal runes. If you have PhD it will only increase one stat, Can be used multiple times, but every time you use it, it has a chance to disappear, The Gold Pill can spawn as a Horse Pill, which then causes it to give random Horse pill effects, UNLOCK: Unlock this by defeating Mega Satan as Tainted Cain, Horse Pills rarely spawn as larger versions of normal pills with more powerful effects, Items that synergize with pills also have the same effect with Horse pills, In general, the effect of a Horse Pill is double the effect of a normal pill i.e. (2% chance for the end of room drop to become a trinket), If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. Stat options are: +1.0 Damage, +0.6 Tears, +0.2 Speed, +5.25 Range, Also drops either a bomb, a key or 3 coins on the ground. The pick-ups which are NOT items, are the Pills, Tarot Cards and Trinkets. After dealing enough damage it will eventually disappear, At full size the flame deals 6x your tear damage, scaling down to 3x at its smallest size, The chance to for each tear to become a flame is affected by your luck stat and at +10 Luck it will activate 50% of the time (starts at 8.33% at +0 Luck), Each tear now has a small chance (3.33%) to be a needle instead, which deals 3 times your tear damage, If a needle hits a non-boss enemy it will instantly kill it and will explode into a circle of 10 more needles, The 10 spawned needles will also deal 3 times your tear damage, but won't instantly kill enemies or explode into more needles, The chance to for each tear to become a needle is affected by your luck stat and at +15 Luck it will activate 50% of the time, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lilith, *, black, syringe, injection, euthansia, dang, dan gheesling, dangheesling, dangDEB8, you piece, Upon entering a new room, Isaac will become camouflaged and enemies won't attack until you start firing tears, Camo Undies grants +0.5 speed while cloaked, When uncloaking, all nearby enemies take damage, and Isaac gains a brief tears + damage up, *, pink, purple, goggles underwear under wear, Any time a devil or angel room door opens after a boss, the other one will also spawn, The extra door will only spawn if a devil or angel room was randomly chosen to spawn already, After entering one of the doors, the other will disappear, If there isn't an available wall for the extra door to spawn on, only one door will spawn (i.e. Each use also gives +0.5 Black Hearts, however this is stays between rooms unlike the other effects, Allows Isaac to deal 40 contact damage to enemies for the current room. The spear occasionally inflicts fear on enemies it damages. For more awesome indie content, subscribe to the channel here and follow me on Twitch for my livestreams!http://www.twitch.tv/pentahybridYou can also join ou. More items consumed = more chance for this effect. ?, Satan and The Lamb as Tainted Magdalene, The first time you pick this trinket up, the heart container will be filled. This includes damage you deal, and environmental damage they take e.g. These will more than usually harm you than help you. REPENTANCE - Bob's Brain now has an increased delay before becoming available when entering rooms. Doesn't include Curse Room doors or spiked rocks, Tears can be controlled mid-flight using the directional keys, In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him, Fully heals all your red heart containers, Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it, The visual effect is similar to the effect given to tears by the GodHead item, The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac, In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect, The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades, Upon taking damage, you have a chance to dislodge the spider from your face. Has a small chance to take you to the I AM ERROR room, and a smaller chance to teleport to a Black Market, Addicted - Causes you to take a full heart of damage for all sources for the current room. The item called Zodiac does not count. The first and second familiars spawn after 15 hits, then 30 hits for the third and fourth, Cambion Conception cannot grant more than 4 familiars in total, UNLOCK: Unlock this item by beating ??? When used, this card drops all of your hearts (including non-red hearts), coins, keys and bombs on the floor, This effect is done in the most efficient way possible - e.g. UNLOCK: Unlock this item by beating the Boss Rush with Azazel, * devil pool, devil room pool, devil deal, grey, gray, bloody, Spawns a trapdoor at Isaac's feet which allows him to travel to the next floor, Digging in certain spots with objects or markings on the floor will guarantee a crawlspace once per floor, In Sheol, Cathedral, Chest and Dark Room this item either opens a Crawl Space, or does nothing, Cannot spawn a trapdoor directly infront of a secret room entrance, Can destroy rocks if used when Isaac is flying over a rock, * secret room pool, devil pool, devil room pool, devil deal, silver, grey, gray, dig, spade, shovel, Counts as 1 of 3 astrology items needed in the same run to unlock Planetariums, * shop room pool, shop item pool, item room, treasure room, item room pool, brown, pink, When used, spawns a Monstro which will jump on a random enemy in the room, dealing 120 damage and destroying nearby obstacles, UNLOCK: Unlock this item by beating the Basement II for the first time, * item room, treasure room, item room pool, white, grey, gray, bloody, monstros tooth, monstro tooth, Everytime you fire a tear, there is a chance that you will also fire three more tears in all cardinal directions, The chance to fire 4-way tears is affected by your luck stat and at +15 Luck it will activate every time, At +0 luck the effect has a 30% chance to activate, UNLOCK: Unlock this item by beating Lokii for the first time, * item room, treasure room, item room pool, grey, gray, devil, lokis horns loki horns, A familiar that follows Isaac and charges forwards, dealing 3.5 damage per tick to any enemies it comes into contact with, REPENTANCE - The damage tick rate on Little Chubby has been increased, UNLOCK: Unlock this item by beating the Caves II for the first time, * item room, treasure room, item room pool, yellow, smile, face, bug, Tears now have a chance of slowing enemies and their projectiles for 2.5 seconds, The chance to slow enemies is affected by your luck stat and at +15 Luck it will activate every time, * item room, treasure room, item room pool, black, grey, gray, red, bug, Has a chance to drop when exploding a tinted rock, UNLOCK: Unlock this item by destroying 100 tinted rocks, * tinted rock, marked rock, grey, gray, lump, white, Reveals adjacent rooms up to 2 rooms away, this includes revealing if you're next to a Secret Room or Super Secret Rooms, Gives Isaac a slight glow when Curse of Darkness is active, Blocks damage from projectiles falling from above, * item room, treasure room, item room pool, spelunky, miner, mining, helpmet, light, purple, olmec yama

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